![]() MSNs did not show significant toxicity in various concentrations (0-500 μg/ml) on Caco- 2 cells. The cytotoxicity of MSNs and MSNs-GA at low and high concentrations were studied by means of 3- 2,5-diphenyltetrazolium bromide (MTT) test and flow cytometry. MSNs were synthesized and loaded with GA, then characterized using transmission electron microscopy (TEM), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy, N 2 adsorption isotherms, X-ray diffraction, and thermal gravimetric analysis. ![]() In this study, the effects of intracellular delivery of various concentrations of gallic acid (GA) as a semistable antioxidant, gallic acid-loaded mesoporous silica nanoparticles (MSNs-GA), and cellular uptake of nanoparticles into Caco- 2 cells were investigated. Rashidi, Ladan Vasheghani-Farahani, Ebrahim Soleimani, Masoud Atashi, Amir Rostami, Khosrow Gangi, Fariba Fallahpour, Masoud Tahouri, Mohammad Taher A cellular uptake and cytotoxicity properties study of gallic acid-loaded mesoporous silica nanoparticles on Caco- 2 cells
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